The drug can be easily made in small clandestine laboratories, with relatively inexpensive over-the-counter ingredients such as pseudoephedrine, a common ingredient in cold medications. This methamphetamine is highly pure, potent, and low in price. How Do Manufacturers Make Methamphetamine?Ĭurrently, most methamphetamine in the United States is produced by transactional criminal organizations (TCOs) in Mexico. increased blood pressure and body temperature.increased wakefulness and physical activity.Taking even small amounts of methamphetamine can result in many of the same health effects as those of other stimulants, such as cocaine or amphetamines. The drug’s ability to rapidly release high levels of dopamine in reward areas of the brain strongly reinforces drug-taking behavior, making the user want to repeat the experience. Dopamine is involved in body movement, motivation, and reinforcement of rewarding behaviors. Methamphetamine increases the amount of the natural chemical dopamine in the brain. How does methamphetamine affect the brain? In some cases, people take methamphetamine in a form of binging known as a "run," giving up food and sleep while continuing to take the drug every few hours for up to several days. injecting the powder that has been dissolved in water/alcoholīecause the "high" from the drug both starts and fades quickly, people often take repeated doses in a "binge and crash" pattern.NIDA Image How do people use methamphetamine?
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